The present study is based on the Theory of Sense of Coherence. Sense of coherence is the ability of individuals to cope with stress and ensure health during traumatic life incidents. The study examined the moderating role of resilience between sense of coherence and psychological problems including depression, anxiety, stress and PTSD among the victims of suicide bombing. Moderating effect of the domains of resilience including trait and state resilience was also examined. The study comprised of a purposive sample of the victims of suicide bombing (N = 300) with age ranges from 30 to 45 years (M = 12.23, SD = 6.73) further divided along gender lines. Data was taken using Sense of Coherence Scale, Trait-State Resilience Inventory, Depression Anxiety Stress Scale and Impact of Events Scale. Hierarchical regression revealed that resilience significantly moderated the relationship between sense of coherence and psychological problems including depression, anxiety and stress among victims of suicide bombing. More specifically, resilience moderated between sense of coherence and PTSD among victims of suicide bombing. Trait and state resilience also moderated between sense of coherence and psychological problems among victims of suicide bombing. Similarly, trait and state resilience also moderated between sense of coherence and PTSD. The study confirmed that the interacting effect of the sense of coherence and resilience on reducing psychological disorders resulted from a severe traumatic experience. The study also shed light on the dual functions of resilience―an ability to recover from trauma and stressful incidents of life. Along with sense of coherence, the moderating effect of resilience inbuilt in an individual’s personality (trait resilience) as well as the resilience gained to respond to a trauma (state resilience) remained helpful in reducing the resultant psychological disorders emerging as an aftermath of becoming victims of suicide bombings in Pakistan.